Tuesday, September 28, 2021

Ivermectin vs. COVID-19

Ivermectin vs. COVID-19

This is a collection of papers and resources I've accumulated about the drug Ivermectin and its use against COVID-19.  This drug is safe, cheap (patent-expired), widely available, FDA approved for many uses, classified by the WHO as "essential medicine", and extremely effective against SARS-CoV-2 and COVID-19, both as prophylaxis and in every stage of the disease.  Ivermectin has even proven to be effective against cancer. One can only speculate as to why the media has not picked up on this but it is becoming increasingly clear that there is big money to be lost if the public finds out.

For my page of Ivermectin news articles, click here.  

For Ivermectin videos, click here.

One word of caution, there is a genetic mutation in a certain percentage of the population that inhibits metabolism of Ivermectin.  (See this study for more details.)  If Ivermectin doesn’t work for you, you may want to try Fluvoxamine.

This page will be updated as new information comes in.

Ivermectin Resources 


A continuation of a timeline of ivermectin-related events in the COVID-19 pandemic


The Pharmacokinetics and Interactions of Ivermectin in Humans—A Mini-review



Bayesian hypothesis testing and hierarchical modelling of ivermectin effectiveness in treating Covid-19

Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials

Effect of Ivermectin in the Treatment of Coronavirus Disease 2019: A Trial Sequential Analysis Highlights the Requirement of Additional Randomized, Controlled Trials



Preliminary meta-analysis of randomized trials of ivermectin to treat SARS- CoV-2 infection 

A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication?

Safety of high-dose ivermectin: a systematic review and meta-analysis (pre-Covid) 





Hospitalized and Outpatient  








Reply to “Ivermectin Treatment May Improve the Prognosis of Patients with COVID-19”

Effects of Ivermectin-azithromycin-cholecalciferol combined therapy on COVID-19 infected patients: A proof of concept study

Comparison of Viral Clearance between Ivermectin with Doxycycline and Hydroxychloroquine with Azithromycin in COVID-19 Patients

COVID-19 Papers      




The BIRD Recommendation on the Use of Ivermectin for Covid-19










Ivermectin: A Closer Look at a Potential Remedy

Ivermectin as a promising RNA-dependent RNA polymerase inhibitor and a therapeutic drug against SARS-CoV2: Evidence from in silico studies

Self-medication during COVID-19 outbreak: a cross sectional online survey in Dhaka city


Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats

Ivermectin: Potential Role as Repurposed Drug for COVID-19

HIV-1 versus SARS-CoV-2 infection: understanding the population genetic aspects of drug inefficacy (especially ivermectin) in the integrase-importin complex

Antiviral Activity of Ivermectin Against SARS-CoV-2: An Old-Fashioned Dog with a New Trick—A Literature Review

White paper on Ivermectin as a potential therapy for COVID-19

Effective Anti-SARS-CoV-2 RNA Dependent RNA Polymerase Drugs Based on Docking Methods : The Case of Milbemycin, Ivermectin, and Baloxavir Marboxil

Has Ivermectin Virus-Directed Effects against SARS-CoV-2? Rationalizing the Action of a Potential Multitarget Antiviral Agent

Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2 

Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: trends, scope and relevance

A comprehensive review on epidemiology, aetiopathogenesis, diagnosis and treatment of the novel coronavirus syndrome – COVID-19

Molecular Docking and Molecular Dynamic Study of two Viral Proteins associated with SARS-CoV-2 with Ivermectin

Nsp7 and Spike Glycoprotein of SARS-CoV-2 are envisaged as Potential Targets of Vitamin D and Ivermectin

Ivermectin for COVID-19 Treatment: Clinical Response at Quasi-Threshold Doses Via Hypothesized Alleviation of CD147-Mediated Vascular Occlusion

Evaluation of diversity levels in HIV-1 virus integrase gene sequences, supporting the lack of target specificity of ivermectin versus the integrase-importin complex in SARS-CoV-2 inflection

Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

The broad spectrum antiviral ivermectin targets the host nuclear transport importinα/β1 heterodimer

Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2

Hydroxychloroquine and ivermectin: A synergistic combination for COVID-19 chemoprophylaxis and treatment?

A Combination of Ivermectin and Doxycycline Possibly Blocks the Viral Entry and Modulate the Innate Immune Response in COVID-19 Patients

A Wonder Drug in the Arsenal against COVID - 19: Medication Evidence from Ivermectin

Antimalarials for COVID-19 Treatment: Rapid Reversal of Oxygen Status Decline with the Nobel Prize-Honored Macrocyclic Lactone Ivermectin

Battle against Coronavirus: Repurposing old friends (Food borne polyphenols) for new enemy (COVID-19)

Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19 

Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen.  

Ivermectin: potential candidate for the treatment of Covid 19

Coronavirus (2019-nCoV) Deactivation via Spike Glycoprotein Shielding by Old Drugs, Bioinformatic Study

Ivermectin, antiviral properties and COVID-19: a possible new mechanism of action

An Overview of Possible Therapeutic Approaches Against Novel Coronavirus Disease 2019 Pandemic

Binding Mechanism and Structural Insights into the Identified Protein Target of Covid-19 with In-Vitro Effective Drug Ivermectin

Ivermectin: repurposing a multipurpose drug for Venezuela's humanitarian crisis

Repurposing Ivermectin to inhibit the activity of SARS CoV2 helicase: possible implications for COVID 19 therapeutics

Repurposing approved drugs as inhibitors of SARS-CoV-2 S-protein from molecular modeling and virtual screening

Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies.

COVID-19 Infections and Africa: Why Do the African Countries Show the Least Number of Cases?

Mass Drug Administration and Worms Experience in Africa: Envisage Repurposing Ivermectin for SARS-COV-2

Ivermectin for Covid-19

The Battle against COVID 19 Pandemic: What we Need to Know Before we “Test Fire” Ivermectin

Ivermectin for COVID-19: A living systematic review protocol

Continuous high-dose ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection

Ivermectin as a Potential Therapeutic Agent for COVID-19 – case studies


Combating COVID-19 Pandemic in Bangladesh: A Memorandum from Developing Country

Proposal To Halt The COVID-19 Pandemic With Ivermectin

Papers on other diseases (for more on Ivermectin vs. Cancer see here.)